Betaxon AL 1577A (2s)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride LEVOBETAXOLOL HYDROCHLORIDE

Name	(2S)-1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol,hydrochloride
Synonyms	Betaxon AL 1577A AL-1577A Levobetaxolol HCL (S)-BETAXOLOL HYDROCHLORIDE Levobetaxolol hydrochloride (2S)-1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol,hydrochloride 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride, (S)- 2-Propanol, 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-, hydrochloride, (2S)- Betaxon AL 1577A (2s)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride LEVOBETAXOLOL HYDROCHLORIDE
CAS	116209-55-3

Molecular Formula	C18H29NO3.ClH
Molar Mass	343.892
Boling Point	448ºC at 760 mmHg
Flash Point	224.7ºC
In vitro study	Levobetaxolol produced potent antagonistic activity at cloned human β1 and β2 receptors, as well as Guinea pig atrial β1, tracheal β2 and rat colon β3 receptors, with an IC50 of 33.2 nM, respectively, 2970 nM and 709 nM. Levobetaxolol (K I = 16.4 nM) was more effective than Dextrobetaxolol(K I = 2.97 μm) in inhibiting Isoproterenol-induced cAMP production in human non-pigmented ciliary epithelial cells. Levobetaxolol (applied topically) protects retinal ganglion cells from different types of injury. Levobetaxolol acts on the rat cortex, replacing [
In vivo study	Levobetaxolol(150 mg) was more effective than Dextrobetaxolol in macaques with ocular hypertension, reducing IOP by 25.9 percent. Levobetaxolol(20 mg/kg) treatment of light-induced retinopathy in rat models significantly protected retinal function, resulting in significant thickening of the RPE and outer nuclear layer. Levobetaxolol(20 mg/kg) caused a 10-fold upregulation of bFGF and a 2-fold upregulation of CNTF mRNA levels, all of which inhibited retinal degeneration in many species.

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Product Name: Betaxolol Impurity 13 Visit Supplier Webpage Request for quotation
CAS: 116209-55-3
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

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Betaxon AL 1577A (2s)-1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol hydrochloride LEVOBETAXOLOL HYDROCHLORIDE Request for Quotation